International Journal of Nursing Studies
Volume 41, Issue 3 , Pages 321-330, March 2004

The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia

  • Kuei-Ru Chou

      Affiliations

    • National Defense Medical Center, School of Nursing, No. 161, Sec. 6 Min-Chuan East Road, Nei-Hu, Taipei 114, Taiwan, ROC
    • Corresponding Author InformationCorresponding author. Tel.: +886-2-87923100; fax: +886-2-87923109
    • ,
  • Ruey Chen

      Affiliations

    • Nursing Department, Tri-Service General Hospital, Taiwan, ROC
    • ,
  • Jia-Fu Lee

      Affiliations

    • Department of Psychiatry, Armed Forces Pei-Tou Hospital, Taiwan, ROC
    • ,
  • Chih-Hung Ku

      Affiliations

    • National Defense Medical Center, Taiwan, ROC
    • ,
  • Ru-Band Lu

      Affiliations

    • Psychiatric Department, Tri-Service General Hospital, Taiwan, ROC

Received 28 January 2003; received in revised form 30 June 2003; accepted 14 July 2003.

Abstract 

The purpose of this study was to determine the effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia. This was a longitudinal study and sixty-eight schizophrenic patients were assigned to 8 weeks of a nicotine-patch therapy program or a control group. The generalized estimating equation analysis revealed that there were significant reductions in the subjects’ nicotine dependence (Fagerstrom Tolerance Questionnaire), the number of cigarettes per day, and CO levels over an 8-week period of nicotine-patch therapy and 3-month follow-up. The point-prevalence rates of abstinence from smoking were an abstinence of 26.9% at 8 weeks and 26.9% at a 3-month follow-up. At the 3-month follow-up, the rate of continuous smoking abstinence in the nicotine-patch group was 23.1%.

Keywords:  Nicotine-patch therapy, Schizophrenia, Smoking cessation

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PII: S0020-7489(03)00168-8

doi:10.1016/j.ijnurstu.2003.07.001

International Journal of Nursing Studies
Volume 41, Issue 3 , Pages 321-330, March 2004

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